Lab News

  • March, 2017 - The TRACD lab is currently looking for a highly motivated and skilled post-doc. Please contact Karyn Hamilton or Ben Miller for more information.
  • Febuary, 2017 - Congratulations to TRACD Post-doc Adam Konopka on his acceptance of a position as Assistant Professor in the Department of Kinesiology and Community Health, University of Illinois!
  • Febuary, 2017 - Congratulations to TRACD PhD Student Chris Wolff on his acceptance of a post-doctoral fellowship at the University of Florida, where he will be working with Dr. Karyn Esser.
  • January, 2017 - Congratulations TRACD PhD student Rob Musci who will receive the Caroline tum Suden/Frances Hellebrandt Professional Opportunity Award at Experimental Biology
  • January, 2017 - Congratulations TRACD Post-doc Melissa Linden who will receive the APS EEP Postdoctoral Research Award at Experimental Biology.
  • January, 2017 - Chris Wolff gave a seminar at the University of Colorado Denver, Department of Integrative Biology.
  • December, 2016 - A recent documentary, Being 'n Motion, features exclusive interviews with Drs. Miller and Hamilton!

What we study and how we study it!

We take an integrative approach to studying age-associated chronic diseases. We are primarily focused on how to maintain muscle, both skeletal and cardiac, over the lifespan. Special areas of focus include proteostatic mechanisms, mitochondria, redox balance, protein stability, and hypoxia. Finally, we focus on strategies that incorporate nutritional strategies as well as exercise for the prevention and treatment of chronic disease.

Through the combined expertise of the lab co-directors we are able to address research questions using cell culture, animal models, in vivo human studies, and clinical interventions. We have established cardiac, skeletal muscle, and human coronary endothelial cell models. Additionally, we use long-lived animal models and animal models for hypoxia, myocardial ischemia-reperfusion, exercise training, and voluntary physical activity. In human subjects we rely on stable isotopic tracer techniques as well as tissue sampling. Cells and tissues are analyzed using a variety of biochemical and molecular techniques.

Lab Updates